Plant Transcription Factor Database
Previous version: v3.0
Gossypium hirsutum
YABBY Family
Species TF ID Description
Gh_A01G0376YABBY family protein
Gh_A01G1348YABBY family protein
Gh_A03G0924YABBY family protein
Gh_A04G0351YABBY family protein
Gh_A05G0082YABBY family protein
Gh_A06G0472YABBY family protein
Gh_A07G0308YABBY family protein
Gh_A07G1044YABBY family protein
Gh_A07G1363YABBY family protein
Gh_A09G0958YABBY family protein
Gh_A11G0723YABBY family protein
Gh_A12G1991YABBY family protein
Gh_D01G1535YABBY family protein
Gh_D01G2326YABBY family protein
Gh_D02G1305YABBY family protein
Gh_D05G0144YABBY family protein
Gh_D05G3293YABBY family protein
Gh_D06G0514YABBY family protein
Gh_D07G0365YABBY family protein
Gh_D07G1125YABBY family protein
Gh_D07G1471YABBY family protein
Gh_D11G0842YABBY family protein
Gh_D12G2170YABBY family protein
YABBY Family Introduction

Members of the YABBY gene family are characterized by two conserved domains, a C2C2 zinc finger-like domain towards the amino terminus and a helix-loop-helix, which we have called the YABBY domain, with sequence similarity to the first two helices of the HMG box towards the carboxyl end of the protein. In addition to the conserved YABBY and zinc finger domains, YAB1, YAB2, YAB3 and YAB5 display some sequence similarity on the carboxyl side of the YABBY domain. The region between the YABBY and zinc finger domains is variable amongst family members.

The presence of these domains suggests these proteins function as transcription factors. Database searches suggest that this family may be plant-specific, as genes with a similar arrangement of zinc finger and YABBY domains do not occur in either Caenorhabditis elegans or Saccharomyces cerevisiae.

The YABBY gene are expressed in a polar manner in all lateral organs produced by apical and flower meristems. Their transcripts are detectable only in the abaxial domains of lateral organs when their primordia emerge and begin to differentiate. Loss of polar expression of these genes results in loss of polar differentiation of cell types in lateral organs, and gain-of-function alleles result in abaxialization of lateral organs. The expression of these genes is precisely correlated with abaxial cell fate in mutants in which abaxial cell fates are found ectopically, reduced or eliminated. We propose that members of this gene family act redundantly to specify abaxial identity in lateral organs produced by the apical and flower meristems in Arabidopsis.

Siegfried KR, Eshed Y, Baum SF, Otsuga D, Drews GN, Bowman JL.
Members of the YABBY gene family specify abaxial cell fate in Arabidopsis.
Development. 1999 Sep;126(18):4117-28.
PMID: 10457020